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Updated: May 31, 2026
10:19
A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Is neonatal group B streptococcal infection preventable?
M Azam1, N M Allen, D O'Donovan
1Department of Paediatrics, Galway University Hospital, Newcastle Road, Galway.
Irish Medical Journal
|July 9, 2011
Summary
Early onset group B streptococcal (EOGBS) infection remains a concern. This study found a low incidence of EOGBS at Galway University Hospital, with limited opportunities to improve intrapartum antibiotic (IAP) use for prevention.
Area of Science:
- Obstetrics and Gynecology
- Neonatal Medicine
- Infectious Diseases
Background:
- Early onset group B streptococcal (EOGBS) infection is a major cause of newborn illness and death.
- Galway University Hospital (GUH) employs a risk-based approach to prevent EOGBS.
Purpose of the Study:
- To determine the incidence of EOGBS at GUH between 2004 and 2009.
- To identify any missed opportunities for preventing neonatal EOGBS infections.
Main Methods:
- Retrospective review of EOGBS cases and intrapartum antibiotic (IAP) administration.
- Analysis of obstetric practices and potential for improved IAP usage.
Main Results:
- The incidence of EOGBS was 0.45 per 1,000 live births.
- One neonatal death and one case with neurological sequelae were recorded.
- Only one mother received IAP; no clear opportunities for improving IAP use were identified.
Conclusions:
- The incidence of EOGBS at GUH during the study period was low.
- Current risk-based obstetric practices may be effective, but further evaluation of IAP strategies is warranted.
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