Related Experiment Video
Updated: May 31, 2026
Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
Published on: September 5, 2011
Prediction of outcome in dichorionic twin pregnancies at 6-10 weeks' gestation
George I Papaioannou1, Argyro Syngelaki, Nerea Maiz
1Fetal Medicine Unit, King's College Hospital, London, England, UK. papaioannougk@gmail.com
Objective:
The objective of the study was to predict the outcome of dichorionic (DC) twin pregnancies at 6-10 weeks' gestation from intertwin discordance in crown-rump length (CRL), heart rate (HR), and gestational sac diameter (GSD).
Study Design:
Intertwin discordance in CRL, HR, and GSD, was compared in 3 groups of DC twin pregnancies with 2 live embryos at 6-10 weeks. In one group, there were 2 live births (n = 174), in another 1 live birth (n = 24), and in a third group there were no live births (n = 33). Regression analysis was used to determine the predictors of outcome.
Results:
Significant contributors to the prediction of 1 intrauterine death were discordance in CRL and GSD. The only predictor of 2 deaths was discordance in CRL. Detection rates of screening for single or double death, at 10% false-positive rate, were 79.2% and 27.3%, respectively.
Conclusion:
In DC twins, intertwin discordance in CRL and GSD at 6-10 weeks can predict outcome.
Related Concept Videos
01:27Ovarian Cycle
02:46Chi-square Analysis
The chi-square test was developed by Pearson in 1990.
The first step of performing a Chi-square analysis is to establish a null hypothesis, which assumes that there is no real...