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Recommendation for the use of newly introduced Tdap vaccine in Korea
Kyong Min Choi1, Kyung Hyo Kim, Yae-Jean Kim
1The Committee on Infectious Diseases, the Korean Pediatric Society, Korea.
Insights
The Tdap vaccine, a booster for tetanus and diphtheria, helps reduce pertussis incidence and transmission in adolescents and adults. Two Tdap vaccines are approved in Korea for individuals aged 11-64.
Area of Science:
- Immunology
- Infectious Diseases
- Vaccinology
Background:
- Pertussis, or whooping cough, is a respiratory infection with a characteristic cough.
- Vaccination with DTwP/DTaP has reduced pertussis, yet outbreaks persist in infants, adolescents, and adults.
- Rising pertussis cases led to the development of the Tdap vaccine for older age groups.
Purpose of the Study:
- To summarize recommendations for Tdap vaccine use in Korea.
- To address the resurgence of pertussis in specific populations.
Main Methods:
- Review of recommendations from the Korean Pediatric Society's Committee on Infectious Diseases.
- Identification of approved Tdap vaccines in Korea.
Main Results:
- Two Tdap vaccines, ADACEL™ and BOOSTRIX®, are approved in Korea.
- These vaccines are indicated for individuals aged 11-64.
Conclusions:
- Tdap vaccination is recommended for adolescents and adults to control pertussis.
- The approved vaccines aim to decrease pertussis incidence and transmission in Korea.
Abstract:
Pertussis is an acute respiratory infection characterized by paroxysmal cough and inspiratory whoop for over 2 weeks. The incidence of pertussis has decreased markedly after the introduction of DTwP/DTaP vaccine, but the incidence of pertussis has increased steadily among young infant and among adolescents and adults in many countries. Td vaccine was used in this age group but the increase in pertussis has lead to the development of a Tdap vaccine. The Tdap vaccine is a Td vaccine with a pertussis vaccine added and is thought to decrease the incidence and transmission of pertussis in the respective age group. In Korea, two products are approved by the KOREA FOOD & DRUG ADMINISTRATION, which are ADACEL™ (Sanofi-Pasteur, Totonto, Ontario, Canada) and BOOSTRIX® (GlaxoSmithKline Biologicals, Rixensart, Belgium) for those aged between 11-64. This report summarizes the recommendations approved by the Committee on Infectious Diseases, the Korean Pediatric Society.
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