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08:49
Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
Published on: May 11, 2018
Biventricular assist devices: a technical review.
Shaun D Gregory1, Daniel Timms, Nicholas Gaddum
1School of Engineering Systems and Medical Device Domain, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD 4001, Australia. shaun.gregory@qut.edu.au
Annals of Biomedical Engineering
|July 9, 2011
Summary
Biventricular assist devices (BiVADs) offer an alternative for end-stage heart failure when donor organs are scarce. Newer implantable BiVADs aim to improve quality of life, though control strategies require refinement.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Devices
Background:
- End-stage heart failure often requires transplantation, but donor organ shortages necessitate mechanical circulatory support.
- Left ventricular assist devices (LVADs) are common, but up to 50% of recipients develop right ventricular failure, requiring biventricular assist devices (BiVADs).
Purpose of the Study:
- To provide a technical review of clinically applied and developing biventricular assist devices (BiVADs).
- To discuss the evolution of BiVAD technology from first-generation to newer implantable systems.
Main Methods:
- Review of existing literature and clinical data on first-generation pulsatile paracorporeal BiVADs.
- Analysis of emerging second and third-generation implantable rotary BiVADs utilizing advanced bearing and levitation systems.
Main Results:
- First-generation BiVADs, while life-saving, are bulky, external, and associated with complications like infection and thrombus formation.
- Newer rotary BiVADs offer potential for fully implantable, long-term solutions but require improved control strategies for volume balancing.
Conclusions:
- Biventricular assist devices (BiVADs) are crucial for patients with biventricular failure, offering an alternative to heart transplantation.
- Continued development of implantable BiVADs promises an improved quality of life for patients with total heart failure.
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