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Updated: May 31, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

Getting the right information to the table: using technology to support evidence-based decision making.

Lynda Atack¹, Patrick Gignac, Malcolm Anderson

¹School of Community and Health Studies, Centennial College, Scarborough, Ontario, Canada. latack@centennialcollege.ca

Healthcare Management Forum

|July 12, 2011

Summary

Healthcare executives found a virtual desktop effective for accessing research and supporting evidence-informed practice, despite some limitations. This technology aids decision-making by improving access to relevant scientific literature.

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Area of Science:

Health Informatics
Information Science
Healthcare Management

Background:

Healthcare executives face challenges accessing relevant research literature.
Difficulty in finding pertinent studies hinders evidence-informed practice.
The EXTRA program aimed to improve research accessibility for executives.

Purpose of the Study:

To explore the utilization of a virtual desktop environment by healthcare executives.
To assess the perceived effectiveness of the virtual desktop in supporting evidence-informed practice.
To identify limitations and benefits of the virtual desktop for healthcare decision-making.

Main Methods:

A study involving healthcare executives enrolled in the EXTRA program.
Exploration of their use of a virtual desktop environment.
Qualitative and quantitative assessments of user experience and perceived utility.

Main Results:

The virtual desktop environment was generally perceived positively by participants.
Despite design and function limitations, the tool was effective.
It successfully supported evidence-informed practice and decision-making processes.

Conclusions:

Virtual desktop environments can be valuable tools for healthcare executives.
Addressing design limitations can further enhance the utility of such technologies.
Improved access to research literature via virtual desktops supports better healthcare decisions.