TGF-β signaling in fibrosis.

Anna Biernacka1, Marcin Dobaczewski, Nikolaos G Frangogiannis

  • 1Division of Cardiology, Albert Einstein College of Medicine, Bronx, NY 14016, USA. nikolaos.frangogiannis@einstein.yu.edu

Summary

Transforming growth factor beta (TGF-β) drives fibrosis by altering fibroblast behavior. Targeting TGF-β pathways is promising for treating fibrotic diseases, but potential side effects require careful consideration.

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