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Retinoic acid promotes transcription of the platelet-derived growth factor alpha-receptor gene
C Wang1, J Kelly, D F Bowen-Pope
1Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts 02115.
Molecular and Cellular Biology
|December 1, 1990
Abstract:
Retinoic acid together with dibutyryl cyclic AMP stimulated transcription of the platelet-derived growth factor alpha-receptor gene in embryonal carcinoma cells (line F9). Processed mRNA transcripts appeared within 4 h after exposure to these agents, and functional alpha:alpha homodimers appeared within 24 h.