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Updated: Sep 16, 2026

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Patch Clamp Recording of Ion Channels Expressed in Xenopus Oocytes
Published on: October 16, 2008
Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes
T J Jentsch1, K Steinmeyer, G Schwarz
1Centre for Molecular Neurobiology (ZMNH), Hamburg University, Germany.
Nature
|December 6, 1990
Abstract:
A complementary DNA encoding a voltage-gated chloride channel from Torpedo marmorata electric organ was cloned by expressing hybrid-depleted messenger RNA in Xenopus oocytes. The predicted protein has a sequence of 805 amino acids containing several putative membrane-spanning domains. Expression of the protein in Xenopus oocytes shows that it is sufficient for channel function.

