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Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Bone Remodeling and Repair01:31

Bone Remodeling and Repair

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Compact Bone01:27

Compact Bone

Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

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Related Experiment Video

Updated: May 31, 2026

Augmented Reality Navigation-Guided Core Decompression for Osteonecrosis of Femoral Head
06:17

Augmented Reality Navigation-Guided Core Decompression for Osteonecrosis of Femoral Head

Published on: April 12, 2022

Core decompression for juvenile osteonecrosis.

José A Herrera-Soto1, Charles T Price

  • 1Division of Pediatric Orthopedics, The Arnold Palmer Hospital for Children, Orlando, FL 32806, USA. jose.herrera@orlandohealth.com

The Orthopedic Clinics of North America
|July 12, 2011
PubMed
Summary
This summary is machine-generated.

Core decompression can aid Legg-Calvé-Perthes disease (LCPD) treatment, especially for older patients classified as having idiopathic juvenile osteonecrosis. This surgical approach may also benefit younger children with LCPD through femoral head fenestration.

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Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
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Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Published on: April 11, 2012

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Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
07:35

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Published on: April 11, 2012

Area of Science:

  • Orthopedics
  • Pediatric Orthopedics
  • Bone Necrosis

Background:

  • Legg-Calvé-Perthes disease (LCPD) is a childhood hip condition.
  • Core decompression is a surgical technique used in treating bone conditions.
  • Avascular necrosis affects bone tissue by disrupting blood supply.

Purpose of the Study:

  • To evaluate core decompression as an adjunctive treatment for Legg-Calvé-Perthes disease (LCPD).
  • To propose a classification and treatment strategy for older LCPD patients.
  • To explore surgical options for juvenile osteonecrosis.

Main Methods:

  • Review of core decompression application in LCPD.
  • Classification of LCPD patients based on age of onset.
  • Comparison with treatment protocols for adult avascular necrosis.

Main Results:

  • Core decompression is recommended for LCPD patients aged 12 years or older.
  • Older patients are classified as idiopathic juvenile osteonecrosis, treated like adult avascular necrosis.
  • Fenestration of the femoral head is suggested for younger LCPD patients.

Conclusions:

  • Core decompression can be a beneficial adjunct treatment for specific LCPD cases.
  • Age-based classification guides treatment for juvenile osteonecrosis.
  • Surgical interventions like core decompression and shelf acetabuloplasty show promise.