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Related Concept Videos

Rolling With Slipping01:14

Rolling With Slipping

Rolling with slipping is a physical phenomenon that occurs when a rolling object experiences both rotational and linear motion but also experiences frictional forces that cause slipping. This phenomenon can occur in various situations, such as when a tire rolls on a wet road or a ball rolls on a rough surface.
An object's rolling motion is characterized by its rotation around its axis, while linear motion refers to the object's translational motion along a surface. Frictional forces can affect...
Rolling Without Slipping01:09

Rolling Without Slipping

People have observed the rolling motion without slipping ever since the invention of the wheel. For example, one can look at the interaction between a car's tires and the surface of the road. If the driver presses the accelerator to the floor so that the tires spin without the car moving forward, there must be kinetic friction between the wheels and the road's surface. If the driver slowly presses the accelerator, causing the car to move forward, the tires roll without slipping. It is essential...
Rolling Resistance01:21

Rolling Resistance

When a solid cylinder rolls steadily on a rigid surface, the normal force applied by the surface on the cylinder is perpendicular to the tangent at the contact point. However, since no materials are entirely rigid, the surface's reaction to the cylinder involves a range of normal pressures.
For instance, imagine a hard cylinder rolling on a comparatively soft surface. The cylinder's weight compresses the surface beneath it. As the cylinder moves, the material in front of it slows down due to...
Rolling Resistance: Problem Solving01:17

Rolling Resistance: Problem Solving

Rolling resistance, also known as rolling friction, is the force that resists the motion of a rolling object, such as a wheel, tire, or ball, when it moves over a surface. It is caused by the deformation of the object and the surface in contact with each other, as well as other factors like internal friction, hysteresis, and energy losses within the materials. Rolling resistance opposes the object's motion, requiring additional energy to overcome it and maintain movement. In practical...
Flow Table Test01:12

Flow Table Test

The flow table test is an established method used to assess the workability of concrete, particularly useful for evaluating highly flowable concrete mixes. This test employs an apparatus that consists of a wooden board topped with a steel plate, collectively weighing 35 pounds. The board is connected to a base via a hinge and measures 27.6 inches on each side.
Concrete is placed within a truncated cone mold that is 8 inches high with an 8-inch base diameter and a 5-inch top diameter. The...
Actin Treadmilling01:18

Actin Treadmilling

Actin filaments undergo polymerization and depolymerization from either end. The polymerization and depolymerization rates depend on the cytosolic concentration of free G-actins. The polymerization rate is generally higher at the plus or barbed end, while the depolymerization rate is higher at the minus or pointed end. At a steady state, critical concentration describes the concentration of free G-actin monomers at which the polymerization rate at the plus end is equal to that of the...

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Imaging Molecular Adhesion in Cell Rolling by Adhesion Footprint Assay
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Imaging Molecular Adhesion in Cell Rolling by Adhesion Footprint Assay

Published on: September 27, 2021

Pass the jelly rolls.

Reza Khayat1, John E Johnson

  • 1Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA.

Structure (London, England : 1993)
|July 12, 2011
PubMed
Summary
This summary is machine-generated.

The vaccinia virus D13 protein

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Last Updated: May 31, 2026

Imaging Molecular Adhesion in Cell Rolling by Adhesion Footprint Assay
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Published on: September 27, 2021

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Area of Science:

  • Structural biology
  • Virology
  • Molecular evolution

Background:

  • The vaccinia virus D13 protein's crystal structure reveals fused "virus jelly roll" folds.
  • These folds are common in double-stranded DNA (dsDNA) icosahedral viruses.

Discussion:

  • The D13 protein, absent in mature vaccinia virus, shares structural similarities with ancient viral ancestors.
  • This suggests an evolutionary link between modern viruses and early icosahedral forms.

Key Insights:

  • The study elucidates the structural basis of viral protein evolution.
  • Identifies conserved structural motifs across diverse dsDNA viruses.

Outlook:

  • Further research into viral protein structures can illuminate evolutionary pathways.
  • Understanding these ancestral structures may aid in developing novel antiviral strategies.