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Published on: November 12, 2019
The rise of cellular therapy
Jacquelyn Choate1, Edward L Snyder
1Department of Laboratory Medicine, Yale University School of Medicine, CT, USA.
Summary
Transfusion Medicine, evolving from Blood Banking, now significantly contributes to Cell Therapy and Regenerative Medicine, leveraging established expertise for new treatments. This expansion offers promising career opportunities in these advanced fields.
Area of Science:
- Transfusion Medicine and Cellular Therapies
- Regenerative Medicine and Stem Cell Transplantation
Background:
- Transfusion Medicine originated as Blood Banking, focusing on blood products for patient transfusion.
- The field has evolved to incorporate apheresis technology and cell therapy, particularly with stem cell transplantation.
- Current advancements position Transfusion Medicine within Regenerative Medicine.
Purpose of the Study:
- To delineate the expanding role of Transfusion Medicine practitioners in Cell Therapy and Regenerative Medicine.
- To highlight the foundational expertise that enables Transfusion Medicine's contribution to these advanced fields.
- To explore the future career prospects within Transfusion Medicine due to its integration with new therapeutic areas.
Main Methods:
- Leveraging existing protocols for therapeutic leukapheresis and mononuclear cell processing.
- Applying established knowledge of current Good Manufacturing Practices (cGMP) and current Good Laboratory Practices (cGLP).
- Utilizing established relationships with clinical departments and understanding of regulatory standards.
Main Results:
- Transfusion Medicine specialists are integral to developing and implementing Cell Therapy and Regenerative Medicine protocols.
- Expertise in cell collection, processing, and regulatory compliance facilitates the integration of Transfusion Medicine into new research.
- The field's involvement now extends to novel treatments for cancer, renal, hepatic, and cardiac illnesses.
Conclusions:
- Transfusion Medicine's historical expertise provides a strong foundation for its expanding role in Cell Therapy and Regenerative Medicine.
- The integration into these advanced fields creates significant opportunities for professional growth and career development.
- The evolution from Blood Banking to encompass Cell Therapy and Regenerative Medicine signifies a dynamic and promising future for the discipline.
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