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Updated: May 31, 2026

A Rat Model of EcoHIV Brain Infection
Published on: January 21, 2021
HIV-related neurocognitive impairment--a review
1Department of Medicine, Mildmay Hospital UK, London, UK. simon.rackstraw@mildmay.org
Abstract:
Neurocognitive impairments following central nervous system opportunistic infections and HIV-associated dementia (HAD) were common clinical features of HIV infection prior to anti-retroviral therapy. As HIV infection has evolved from an invariably fatal disease with a poor prognosis to a condition requiring long-term management, HIV-related neurocognitive disorders have been the subject of increasing research. This review will examine the recent changes in the understanding of the HIV-associated neurocognitive disorders (HAND) including the changing epidemiology, risk factors associated with its development, methods for screening for the disorders and evolving treatment options.
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