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Interaction of lipocortin I with peripheral-type benzodiazepine binding sites
S Mihara1, T Sakata, M Fujimoto
1Shionogi Research Laboratories, Shionogi & Co. Ltd., Osaka, Japan.
European Journal of Pharmacology
|September 18, 1990
Abstract:
Recombinant rat lipocortin I increased [3H]PK 11195 binding to porcine aortic smooth muscle membranes, whereas a polyclonal anti-rat lipocortin I antiserum decreased both basal and lipocortin I-enhanced [3H]PK 11195 binding. The results suggest the possibility of lipocortin I being involved in the function of peripheral-type benzodiazepine binding sites.