Related Experiment Video
Updated: May 31, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Allergic fungal sinusitis with massive intracranial extension presenting with tearing
Animesh Petkar1, Luigi Rao, Daniel R Elizondo
1Department of Ophthalmology, National Naval Medical Center, Bethesda, Maryland 20889, USA.
Abstract:
A 24-year-old male presented with tearing, and subsequent workup and imaging showed a mass with fluid involving the nasopharynx, the paranasal sinuses, and the posterior dehiscence of the left frontal sinus intracranially compressing the frontal lobe significantly. Microscopic examination confirmed the diagnosis of allergic fungal sinusitis. Endoscopic drainage and sinostomy was performed by the otolaryngology (ear-nose-throat) service. The patient was followed 9 months postoperatively and did well with resolution of the epiphora. Although epiphora alone is an unusual presentation of allergic fungal sinusitis, ophthalmologists need to be aware of this entity, as it may invade the orbit through the sinus cavities or compress on the nasolacrimal duct before it causes other mass-related symptoms. Radiology and the characteristic histopathologic findings are the most useful in establishing the correct diagnosis.
Related Concept Videos
Cryptococcal Meningitis
Brain Abscess l: Introduction
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Increased Intracranial Pressure ll: Pathophysiology
Epistaxis
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
