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Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome (ARDS)
06:22

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome (ARDS)

Published on: April 7, 2021

[Prognosis and its affecting factors in children with acute respiratory distress syndrome]

Zhi-Min Niu1, Yan-Hong Li, Shun-Jie Jiang

  • 1Department of Pediatrics, Changyuan People's Hospital, Changyuan, Henan 453400, China. niuzhimin0@126.com

Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics
|July 15, 2011
PubMed

Insights

In children with acute respiratory distress syndrome (ARDS), the highest mortality occurs within 3 days. Age, primary disease, and pediatric critical illness score (PCIS) significantly impact survival outcomes.

Area of Science:

  • Pediatric Critical Care Medicine
  • Respiratory Medicine
  • Neonatology

Background:

  • Acute Respiratory Distress Syndrome (ARDS) is a severe condition in children.
  • Understanding prognosis and influencing factors is crucial for pediatric ARDS management.

Purpose of the Study:

  • To investigate the prognosis of pediatric ARDS.
  • To identify factors affecting survival in children with ARDS.

Main Methods:

  • A cohort of 78 children diagnosed with ARDS was enrolled.
  • Survival status within 30 days was monitored.
  • Cox multiple factors analysis was used to identify risk factors.

Main Results:

  • The 30-day survival rate for pediatric ARDS was 35% (27 survivors out of 78).
  • Mortality peaked within the first 3 days of ARDS onset.
  • Significant differences were observed in age, primary disease, PCIS, and other clinical parameters between survivors and non-survivors.

Conclusions:

  • The critical period for mortality in pediatric ARDS is within the initial 3 days.
  • Age, the nature of the primary disease, and the Pediatric Critical Illness Score (PCIS) are independent predictors of prognosis in pediatric ARDS.
Abstract

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