Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Streptococcal Pharyngitis01:27

Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nutritional status, metabolic state and nutrient intake in children with bronchiolitis.

International journal of food sciences and nutrition·2016
Same author

Optic neuritis associated with influenza B virus meningoencephalitis.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2014
Same author

Biofilms and infections of the upper respiratory tract.

European review for medical and pharmacological sciences·2010
Same author

[Topical treatment of localized edemas of mechanical or inflammatory origin with a novel antiedema ointment. A prospective study].

La Clinica terapeutica·2008
Same author

[Acute rheumatic fever: a report].

Le infezioni in medicina·2003
Same author

Oxatomide in the treatment of atopic dermatitis in breast-fed and very young infants.

Minerva pediatrica·2001

Related Experiment Videos

[Streptococcal tonsillopharyngitis: clinical vs. microbiological diagnosis].

A Boccazzi1, M Garotta, S Pontari

  • 1Fondazione Policlinico Ca Granda IRCCS, Milan, Italy.

Le Infezioni in Medicina
|July 15, 2011
PubMed
Summary

Clinical diagnosis alone misdiagnoses many acute pharyngitis cases. Rapid antigen detection tests (RADT) combined with clinical scoring improve accuracy in identifying streptococcal infections, reducing unnecessary antibiotic use.

Related Experiment Videos

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Diagnostic Medicine

Background:

  • Acute pharyngitis (AP) diagnosis relies on clinical assessment and testing.
  • Accurate identification of streptococcal AP is crucial to prevent complications and antibiotic resistance.

Purpose of the Study:

  • To compare clinical diagnosis versus rapid antigen detection tests (RADT) for identifying streptococcal acute pharyngitis.
  • To evaluate the utility of a modified Breese scoring system in conjunction with diagnostic methods.

Main Methods:

  • 629 children with AP were assessed using clinical judgment and a modified Breese score.
  • Rapid antigen detection tests (RADT) were performed, followed by throat culture for RADT-negative cases.
  • Clinical diagnosis accuracy was determined by sensitivity and specificity.

Main Results:

  • Clinical diagnosis correctly identified AP in 74.2% of cases (sensitivity 81.1%, specificity 70.5%).
  • Scoring systems showed significant intergroup differences between streptococcal and non-streptococcal cases.
  • Clinical judgment alone misdiagnosed a notable percentage of AP cases.

Conclusions:

  • Clinical diagnosis alone is insufficient for accurate AP assessment.
  • Integrating RADT and scoring systems can enhance streptococcal infection identification.
  • Improved diagnostic strategies are essential for optimizing AP treatment and combating antibiotic resistance.