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Updated: May 31, 2026
![Microwave-assisted One-pot Synthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F2755.jpg&w=3840&q=50)
Microwave-assisted One-pot Synthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)
Published on: June 28, 2011
3-Fluoro-4-nitro-phenyl 4-methyl-benzene-sulfonate
This study details the crystal structure of a fluorinated organic sulfur compound, C(13)H(10)FNO(5)S. It reveals specific molecular arrangements including benzene ring stacking and hydrogen bonding in the solid state.
Area of Science:
- Crystallography
- Organic Chemistry
- Materials Science
Background:
- Understanding the solid-state structure of organic compounds is crucial for predicting their physical and chemical properties.
- Fluorinated organic sulfur compounds are of interest due to their potential applications in various fields.
Purpose of the Study:
- To elucidate the crystal structure of the title compound, C(13)H(10)FNO(5)S.
- To analyze intermolecular interactions within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond lengths, bond angles, and intermolecular interactions was performed.
Main Results:
- The dihedral angle between the benzene rings in C(13)H(10)FNO(5)S was determined to be 47.63(14)°.
- π-π stacking interactions were observed between adjacent molecules with a centroid-centroid distance of 3.7806(16) Å.
- Weak intermolecular C-H⋯O hydrogen bonds were identified in the crystal structure.
Conclusions:
- The crystal structure of C(13)H(10)FNO(5)S is characterized by specific dihedral angles and significant π-π stacking.
- The identified intermolecular interactions provide insights into the packing and stability of the compound in the solid state.
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