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Updated: May 31, 2026

Synthesis of High Purity Nonsymmetric Dialkylphosphinic Acid Extractants
Published on: October 19, 2017
Diethyl [(3-cyano-1-phenyl-sulfonyl-1H-indol-2-yl)meth-yl]phospho-nate
Abstract:
In the title compound, C(20)H(21)N(2)O(5)PS, the indole ring is essentially planar, with a maximum deviation of -0.0083 (18) Å. The methyl C atom of the methyl-phospho-nate group and the S atom lie 0.104 (2) and -0.2158 (6) Å, respectively, from the indole mean plane. The sulfonyl-bound phenyl ring is almost perpendicular to the indole ring system, with a dihedral angle of 82.30 (8)°. The ethyl side chains are disordered over two sets of sites, with occupancy factors of 0.737 (5)/0.263 (5) and 0.529 (11)/0.471 (11). In the crystal, mol-ecules are linked into centrosymmetric dimers via C-H⋯O hydrogen bonds, resulting in an R(2) (2)(18) graph-set motif. The crystal structure is further stabilized by C-H⋯π inter-actions.
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