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Updated: May 31, 2026

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
Published on: December 4, 2016
Diethyl 4,6-diacetamido-isophthalate.
Peishen Li1, Xianghui Li, Chao Chen
1Key Laboratory for Radiation Physics and Technology of the Ministry of Education, College of Chemistry, Institute of Nuclear Science and Technology, Sichuan University, Chengdu 610064, Sichuan, People's Republic of China.
This study reveals the crystal structure of a compound, detailing its internal hydrogen bonds and how molecules connect in chains. These findings are crucial for understanding molecular interactions in solid-state chemistry.
Area of Science:
- Crystallography
- Solid-state chemistry
- Molecular structure analysis
Background:
- Understanding intermolecular forces is key to predicting material properties.
- Crystal engineering relies on detailed knowledge of molecular packing and interactions.
Purpose of the Study:
- To elucidate the crystal structure of the title compound C(16)H(20)N(2)O(6).
- To identify and characterize intra-molecular and inter-molecular interactions within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction analysis was performed.
- Structural data was analyzed to identify hydrogen bonding motifs and packing arrangements.
Main Results:
- Two intramolecular N-H⋯O hydrogen bonds forming S(6) rings were identified within the molecule.
- Molecules are linked by intermolecular C-H⋯O hydrogen bonds, forming [001] chains in the crystal structure.
Conclusions:
- The crystal structure is stabilized by a combination of intramolecular and intermolecular hydrogen bonds.
- The identified hydrogen bonding patterns provide insights into the self-assembly and structural characteristics of the compound.
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