Related Experiment Video
Updated: May 31, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
Published on: June 20, 2014
3-Carb-oxy-5-(pyridinium-4-yl)benzoate: a redetermination
Abstract:
The title compound, C(13)H(9)NO(4), crystallizes in a zwitterionic form with the pyridine N atom protonated and the carboxyl OH group deprotonated. The benzene and pyridinium rings are inclined with a dihedral angle of 31.42 (14)° between them. A previous report of this stucture claims, we believe incorrectly, that neither of the carboxyl-ate groups is deprotonated [Zhang et al. (2010 ▶). Acta Cryst. E66, o2928-o2928]. In the crystal, inter-molecular O-H⋯O, N-H⋯O and weak C-H⋯O hydrogen-bonding inter-actions link adjacent mol-ecules into a three-dimensional supra-molecular network.
Related Concept Videos
Reactions at the Benzylic Position: Oxidation and Reduction
Oxymercuration-Reduction of Alkenes
Nucleophilic Aromatic Substitution: Elimination–Addition
![[(DPEPhos)(bcp)Cu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
