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Updated: May 31, 2026

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
Ethyl 8-amino-6-bromoimidazo[1,2-a]pyridine-2-carb-oxy-late
Abstract:
There are two independent mol-ecules in the asymmetric unit of the title compound, C(10)H(10)BrN(3)O(2), which are linked by N-H⋯O and C-H⋯O hydrogen bonds. The fused ring systems in both mol-ecules are nearly planar with maximum deviations of 0.001 (3) and 0.029 (3) Å. All non-H atoms of the first mol-ecule are approximately co-planar whereas in the second mol-ecule, the ethyl group is almost perpendicular to the imidazo[1,2-a]pyridine system, the C-O-C-C torsion angles in the carb-oxy-lic acid ethyl group being -179.8 (4) and 112.1 (5)°, respectively.
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