Adrenalectomy in dogs with adrenal gland tumors: 52 cases (2002-2008)
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Updated: May 31, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Federico Massari1, Stefano Nicoli, Giorgio Romanelli
1Clinica Veterinaria Nerviano, Via Lampugnani 3, Nerviano, 20014 Milan, Italy. fidomas@hotmail.com
Objective:
To evaluate predictors of survival time in dogs undergoing adrenalectomy and identify risk factors associated with adrenal gland tumor metastasis and vein thrombosis.
Design:
Retrospective case series.
Animals:
52 dogs with primary adrenal gland tumors.
Procedures:
Medical records were reviewed. Signalment, tumor features, and information from surgical procedures were evaluated to identify factors predictive of overall survival time, which was defined as the time from surgery until death. The association between metastasis or vein thrombosis and tumor type, size, and site (right or left adrenal gland) was investigated.
Results:
On the basis of results of univariate analysis, survival time was significantly shorter for dogs with adenocarcinoma, tumor major axis length ≥ 5 cm, metastasis, and vein thrombosis and when adrenalectomy was combined with an additional abdominal surgical intervention. On multivariate analysis, survival time was significantly shorter for dogs with an adrenal gland tumor with major axis length ≥ 5 cm and for dogs with metastasis or vein thrombosis. Significant associations were found between metastasis and adenocarcinoma and between vein thrombosis and tumors with major axis length ≥ 5 cm.
Conclusions And Clinical Relevance:
Dogs with an adrenal gland tumor with major axis length ≥ 5 cm, documented metastasis, or vein thrombosis had a poorer prognosis. Metastasis was more frequent in dogs with adenocarcinoma and vein thrombosis when tumors were ≥ 5 cm in length.
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