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Related Experiment Video

Updated: May 31, 2026

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice
09:06

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice

Published on: January 9, 2019

Cortical activations in sequential bilateral cochlear implant users.

K M J Green1, P J Julyan, D L Hastings

  • 1Department of Otolaryngology, Manchester Royal Infirmary, Manchester, UK. kmjgreen@rcsed.ac.uk

Cochlear Implants International
|July 16, 2011
PubMed
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Bilateral cochlear implants do not summate cortical activity; instead, they develop distinct neural networks. The first implant shows stronger auditory recruitment, while the second activates visual areas, revealing unique brain plasticity.

Area of Science:

  • Neuroscience
  • Audiology
  • Medical Imaging

Background:

  • Cochlear implantation is a key treatment for severe to profound hearing loss.
  • Understanding brain plasticity after bilateral cochlear implantation is crucial for optimizing auditory rehabilitation.
  • Previous research has not fully detailed the distinct cortical activation patterns between first and second implants.

Purpose of the Study:

  • To investigate auditory and visual cortical activations in bilateral cochlear implant (CI) recipients.
  • To compare brain activity when using the first CI alone, the second CI alone, and both CIs simultaneously.
  • To explore the neural network development and interactions following bilateral cochlear implantation.

Main Methods:

  • Utilized [(18)F]-FDG positron emission tomography (PET) to measure glucose metabolism in the brain.

Related Experiment Videos

Last Updated: May 31, 2026

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice
09:06

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice

Published on: January 9, 2019

  • Assessed cortical activations in response to auditory stimulation from individual and combined CI use.
  • Analyzed distinct patterns of neural recruitment in auditory and visual cortices.

    • Main Results:

    • Simultaneous activation of both CIs did not result in summation of cortical activity.
    • Distinct neural networks were observed for the first and second CIs.
    • The first CI demonstrated stronger bilateral auditory area recruitment compared to the second CI.
    • Visual cortical activations were observed with the second CI but not the first.
    • No visual activations occurred when both CIs were activated simultaneously, suggesting network interaction.

    Conclusions:

    • Bilateral cochlear implantation leads to the development of distinct, rather than additive, neural networks.
    • The findings highlight significant variability in brain plasticity following cochlear implantation.
    • The differential activation patterns suggest unique functional roles and interactions between first and second CI networks.