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Updated: May 31, 2026
13:46
A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size
Published on: October 17, 2016
Poly-lactic acid synthesis for application in biomedical devices - a review
Astrid J R Lasprilla1, Guillermo A R Martinez, Betânia H Lunelli
1School of Chemical Engineering, State University of Campinas, Campinas, Brazil.
Biotechnology Advances
|July 16, 2011
Summary
Poly-lactic acid (PLA) is an eco-friendly, non-toxic biopolymer derived from renewable resources. This review explores PLA
Area of Science:
- Biomaterials Science
- Polymer Chemistry
- Biotechnology
Background:
- Bioabsorbable polymers offer promising alternatives for medical applications.
- Poly-lactic acid (PLA) is a key biopolymer synthesized from renewable resources like sugarcane.
- PLA exhibits non-toxicity and excellent biocompatibility, making it suitable for in-vivo use.
Purpose of the Study:
- To review lactic acid production via fermentation.
- To examine poly-lactic acid (PLA) synthesis for biomaterial applications.
- To elucidate the relationship between PLA properties, manufacturing, and biomedical utility.
Main Methods:
- Review of fermentation processes for lactic acid production.
- Analysis of various polymer synthesis routes for PLA.
- Examination of PLA's chemical and mechanical properties.
Main Results:
- PLA can be produced from renewable feedstocks, yielding an eco-friendly biomaterial.
- Diverse synthesis methods allow for tunable PLA properties.
- PLA and its copolymers demonstrate excellent biocompatibility and mechanical strength.
Conclusions:
- Understanding PLA's material properties and manufacturing is crucial for optimizing biomedical applications.
- PLA is a versatile biomaterial with significant potential in tissue engineering.
- Further research into PLA synthesis and application is warranted.
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