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Migraine with benign episodic unilateral mydriasis
1Mayo Clinic, Rochester, MN, USA;
International Journal of General Medicine
|July 16, 2011
Summary
Benign episodic unilateral mydriasis causes intermittent pupil asymmetry. This rare condition, potentially linked to migraine, requires thorough neurological evaluation to rule out serious causes.
Area of Science:
- Ophthalmology
- Neurology
Background:
- Pupil asymmetry (anisocoria) presents diverse causes, ranging from benign to malignant, and can be acute or chronic.
- A normal variant in 20% of individuals, anisocoria necessitates careful differentiation.
- Benign episodic unilateral mydriasis is a specific, intermittent cause of pupil asymmetry.
Observation:
- This case report details a 30-year-old female patient with a history of migraines.
- The patient presented with intermittent unilateral pupil dilation (mydriasis).
- Extensive neurological examinations were conducted and yielded negative results.
Findings:
- The diagnosis of benign episodic unilateral mydriasis was established.
- Pathophysiology may involve dysregulation between sympathetic and parasympathetic nervous systems.
- A potential association with migraine, possibly a variant of ophthalmoplegic migraine, is noted.
Implications:
- Highlights the importance of a comprehensive neurological workup for intermittent anisocoria.
- Underscores benign episodic unilateral mydriasis as a distinct clinical entity.
- Contributes to understanding the spectrum of migraine-related neurological phenomena.
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