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Updated: May 31, 2026

Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV

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Published on: November 10, 2023

New respiratory viruses and the elderly.

Laura Jartti¹, Henriikka Langen, Maria Söderlund-Venermo

¹Department of Geriatrics, Turku City Hospital, Turku, Finland.

The Open Respiratory Medicine Journal

|July 16, 2011

Summary

Recent advancements in PCR diagnostics have identified numerous new respiratory viruses. However, viral causes remain underdiagnosed in the elderly, highlighting a critical gap in understanding their clinical significance.

Keywords:

Bocavirus coronavirus elderly influenza virus metapneumovirus polyomavirus respiratory infection torque teno virus.

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Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Published on: April 4, 2019

Area of Science:

Virology
Infectious Diseases
Public Health

Background:

Diagnostic capabilities for respiratory viral infections have significantly advanced over the last 15 years, largely due to PCR techniques.
Several novel respiratory viruses and their subtypes have been identified since 1997, expanding the known spectrum of respiratory pathogens.

Purpose of the Study:

To review newly discovered respiratory viruses and their clinical significance.
To specifically address the underdiagnosis and clinical impact of these viruses in the elderly population.

Main Methods:

Literature review of newly discovered respiratory viruses.
Analysis of clinical significance, with a focus on the elderly and exacerbations of chronic respiratory illnesses.

Main Results:

New viruses like influenza A (H5N1, H1N1), human metapneumovirus, SARS coronavirus, and human bocavirus have emerged.
Viral etiology is identified in nearly all pediatric respiratory illnesses but less than 40% in the elderly and those with chronic respiratory conditions.
These viruses cause a range of symptoms from common cold to pneumonia and acute respiratory failure.

Conclusions:

Despite diagnostic improvements, viral respiratory infections in the elderly are often overlooked.
Further research is needed to elucidate the clinical significance of these emerging viruses in vulnerable elderly populations.