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Updated: May 31, 2026
Orthotopic Left Lung Transplantation in Rats
Published on: July 3, 2025
[Lung transplantation for lung carcinoma: a case report and literature review]
1Department of General Thoracic Surgery, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214023, China.
Background And Objective:
Lung carcinoma is a relative contraindication for lung transplantation (LTx). The improvement of this procedure may successfully treat novel end-stage pulmonary diseases. In the present study, we reported one case of bilateral LTx (BLT) in a young man with bilateral lung carcinoma and reviewed related literature to investigate patient selection and curative effect.
Methods:
A 42-year-old male patient underwent BLT on October 21, 2010 in our hospital. Preoperative chest CT and PET-CT showed bilateral multiple nodules and mass without positive lymph nodes or extrapulmonary metastasis. Bronchioloalveolar carcinoma was identified histologically (T4N0M0, stage IIIb).
Results:
Routine therapies were performed postoperatively. The patient was discharged on post-operative day 66. There was no clinical or radiologic evidence of the recurrence of lung carcinoma in his latest follow-up of 6 months postoperatively.
Conclusions:
LTx may be proposed as an efficient therapeutic option in selected patients of lung carcinoma.
