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A highly sensitive and selective antioxidant probe based on a bi-modally functionalized conjugated polyelectrolyte

Dejun Pei1, Jinqing Hong, Feng Lin

  • 1The Key Laboratory of Analytical Science, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.

Chemical Communications (Cambridge, England)
|July 19, 2011
PubMed

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Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...