Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Systematic review and meta-analysis to identify meropenem exposures and pharmacological targets predictive of clinical outcomes.

The Journal of antimicrobial chemotherapy·2026
Same author

UK Antimicrobial Registry: Virtual Registry-an innovative surveillance approach for monitoring the real-world use and effectiveness of newly licensed antimicrobials in Scotland.

JAC-antimicrobial resistance·2026
Same author

Parental awareness and management of antibiotic side effects and allergies in children and young people: a UK survey.

JAC-antimicrobial resistance·2026
Same author

SUBCUT HF II: rationale and design of a multicentre randomized controlled trial of SUBCUTaneous furosemide to support early discharge in patients admitted to hospital due to Heart Failure.

European journal of heart failure·2026
Same author

Expert Perspectives on Managing Iron Deficiency in People with CKD and/or HF.

Journal of clinical medicine·2026
Same author

Atrial fibrillation and heart failure with preserved ejection fraction: diagnostic challenges and therapeutic opportunities.

Heart (British Cardiac Society)·2026

Related Experiment Video

Updated: May 30, 2026

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat

Published on: June 4, 2012

Enterococcus cecorum aortic valve endocarditis.

Fozia Z Ahmed1, Mirza W Baig, Deborah Gascoyne-Binzi

  • 1Department of Cardiology, Leeds General Infirmary, LS1 3EX Leeds, United Kingdom. foziaahmed@doctors.org.uk

Diagnostic Microbiology and Infectious Disease
|July 20, 2011
PubMed
Summary

This study documents the first human aortic valve infective endocarditis case caused by Enterococcus cecorum. Polymerase chain reaction (PCR) confirmed the pathogen, highlighting its utility in identifying rare causes of endocarditis.

More Related Videos

Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart
08:22

Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart

Published on: April 15, 2020

Related Experiment Videos

Last Updated: May 30, 2026

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat

Published on: June 4, 2012

Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart
08:22

Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart

Published on: April 15, 2020

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Cardiology

Background:

  • Infective endocarditis (IE) is a serious infection of the heart valves, often caused by bacteria.
  • Enterococcus species are known causes of IE, but Enterococcus cecorum is rarely implicated.

Observation:

  • A patient presented with symptoms suggestive of infective endocarditis.
  • Blood cultures yielded Enterococcus cecorum, an unusual pathogen in this context.
  • Initial microbiological identification was challenging, leading to potential misidentification.

Findings:

  • The causative agent of aortic valve endocarditis was confirmed as Enterococcus cecorum.
  • 16S ribosomal gene polymerase chain reaction (PCR) proved crucial for accurate pathogen identification.
  • This case represents the first documented instance of E. cecorum causing human endocarditis.

Implications:

  • Accurate and rapid identification of pathogens like E. cecorum is vital for effective treatment of infective endocarditis.
  • Polymerase chain reaction (PCR) offers a valuable tool for identifying uncommon or difficult-to-culture microorganisms in clinical settings.
  • This case expands the spectrum of known bacterial causes of infective endocarditis and underscores the importance of advanced diagnostic methods.