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Updated: Feb 8, 2026

Left Coronary Artery Ligation: A Surgical Murine Model of Myocardial Infarction
Published on: August 9, 2022
Congenital left main coronary artery aneurysm
Cihan Dundar1, Kursat Tigen, Selcuk Pala
1Department of Cardiology, Kartal Kosuyolu Heart Education and Research Hospital, Denizer C. Cevizli, Kartal, Istanbul, Turkey.
Left main coronary artery aneurysm (LMCAA) is a rare heart condition. This case report details a large LMCAA in a young adult, highlighting congenital causes and associated conditions.
Area of Science:
- Cardiology
- Vascular Medicine
- Congenital Heart Disease
Background:
- Left main coronary artery aneurysm (LMCAA) is a rare coronary artery abnormality, affecting approximately 0.1% of patients undergoing coronary angiography.
- While atherosclerosis is the most common cause in acquired cases, congenital malformations can also lead to LMCAA.
- LMCAA can present as an isolated finding or be associated with other cardiovascular conditions.
Observation:
- A case study involving a 26-year-old female patient with a significantly large LMCAA.
- The patient's initial diagnosis was tetralogy of Fallot, a complex congenital heart defect.
Findings:
- The presented case details a large LMCAA in a young adult female.
- This finding underscores the possibility of congenital etiologies for LMCAA, even in the presence of other cardiac diagnoses.
Implications:
- This case expands the understanding of LMCAA presentation and etiology, particularly in younger populations.
- It suggests the importance of considering congenital factors in the differential diagnosis of coronary artery aneurysms.
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