Two uncommon manifestations of leptospirosis: Sweet's syndrome and central nervous system vasculitis

Area of Science:

• Infectious Diseases
• Neurology
• Dermatology

Background:

• Leptospirosis is a widespread zoonotic spirochetal infection, prevalent in tropical and temperate regions.
• Its varied clinical presentations pose diagnostic challenges for healthcare professionals globally.
• Early clinical suspicion is crucial for diagnosing leptospirosis, especially in resource-limited settings.

Observation:

• This report details two infrequent clinical presentations of leptospirosis.
• The observed uncommon manifestations include Sweet's syndrome and central nervous system (CNS) vasculitis.

Findings:

• Documentation of Sweet's syndrome as a manifestation of leptospirosis.
• Identification of central nervous system vasculitis as a rare complication of leptospirosis.

Implications:

• Increased awareness of these rare presentations can improve diagnostic accuracy for leptospirosis.
• Recognizing unusual symptoms like Sweet's syndrome and CNS vasculitis is vital for timely and appropriate patient management.
• This documentation contributes to a broader understanding of the protean nature of leptospirosis.