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Published on: October 2, 2020
Circadian variations in body temperature during dialysis
Len A Usvyat1, Peter Kotanko, Frank M van der Sande
1Renal Research Institute, New York, NY, USA.
Circadian rhythms influence body temperature changes during hemodialysis (HD), affecting blood pressure. Understanding these thermal shifts is crucial for managing intra-dialytic hypotension.
Area of Science:
- Nephrology
- Chronobiology
- Physiology
Background:
- Hemodialysis (HD) can cause thermal changes impacting patient hemodynamics.
- The precise mechanisms of body temperature increase during HD are not fully understood.
- Circadian variation's role in these temperature changes requires further investigation.
Purpose of the Study:
- To assess the effect of circadian variation on body temperature changes during hemodialysis.
- To compare temperature fluctuations in patients undergoing morning, afternoon, and evening HD shifts.
Main Methods:
- Retrospective observational cohort study using clinical database data from January and August 2008.
- Categorization of body temperature changes by dialysis shift (morning, afternoon, evening).
- Comparison of temperature data across 1064 (morning), 730 (afternoon), and 210 (evening) patients.
Main Results:
- Pre-dialysis temperatures varied significantly across shifts, being highest in the evening.
- Intra-dialytic temperature increases differed significantly between shifts in August, correlating with circadian rhythms.
- Body temperature changes were linked to pre-dialysis temperature, dialysate quality, treatment duration, and dialysate temperature.
Conclusions:
- Dialysis shift timing significantly relates to pre-dialysis and intra-dialytic body temperature changes, aligning with circadian rhythms.
- The connection between body temperature fluctuations and intra-dialytic blood pressure changes may contribute to intradialytic hypotension.
- These findings highlight the importance of considering circadian body temperature rhythms in dialysis management.
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