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Diabetes Insipidus I: Introduction01:29

Diabetes Insipidus I: Introduction

Definition Diabetes insipidus is a disorder marked by the production of large amounts of dilute urine because of impaired vasopressin production, release, or kidney response. The lack of effective vasopressin action limits water reabsorption in the renal collecting ducts, which leads to excessive urinary water loss and intense thirst.Clinical PresentationIndividuals with diabetes insipidus report persistent thirst and very high urine output. In severe cases, fluid intake can reach up to 20...
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Hyperglycemia is an abnormally high blood glucose level. It is diagnosed by fasting glucose ≥126 mg/dL, 2-hour oral glucose tolerance test (or OGTT) ≥200 mg/dL, random glucose ≥200 mg/dL with symptoms, or HbA1c ≥6.5%. However, HbA1c results may be unreliable in certain conditions, such as anemia or hemoglobinopathies, and the diagnosis should be confirmed unless classic symptoms are present. Postprandial hyperglycemia is typically considered significant when glucose levels exceed 180 mg/dL two...
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Hypoglycemia is a blood glucose level below 70 mg/dL. It commonly occurs in individuals using insulin or insulin-secreting drugs, but may also arise in non-diabetic conditions. People with type 1 diabetes are at the highest risk because they depend on exogenous insulin. People with type 2 diabetes are also at risk, especially when treated with insulin or medications such as sulfonylureas, which increase insulin release regardless of blood glucose levels. It develops when insulin levels exceed...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

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Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...

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A Mouse Model of Subchronic and Mild Social Defeat Stress for Understanding Stress-induced Behavioral and Physiological Deficits
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Psychogenic polydipsia.

Ajay Kohli1, Shishir Verma, Ashish Sharma

  • 1Department of Psychiatry, Era's Lucknow Medical College, Lucknow, Uttar Pradesh, India.

Indian Journal of Psychiatry
|July 21, 2011
PubMed
Summary
This summary is machine-generated.

This case report details psychogenic polydipsia, a water-drinking disorder, in an Indian patient diagnosed with depression. Treatment with antidepressant medication led to full recovery and resolution of urinary tract changes.

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Area of Science:

  • Psychiatry
  • Nephrology
  • Endocrinology

Background:

  • Psychogenic polydipsia is a condition characterized by excessive water intake.
  • It is often associated with psychiatric disorders, particularly depression.
  • Limited case reports exist in Indian medical literature.

Purpose of the Study:

  • To report the first case of psychogenic polydipsia in an Indian journal.
  • To highlight the association between depression and psychogenic polydipsia.
  • To describe the diagnostic and management approach.

Main Methods:

  • A case study of a patient diagnosed with depression (ICD 10 R criteria).
  • Comprehensive medical investigations, including assessment for antidiuretic hormone abnormalities and urinary tract changes.
  • Treatment with antidepressant medication.

Main Results:

  • The patient presented with symptoms consistent with psychogenic polydipsia and depression.
  • Investigations revealed reversible urinary tract changes but no hyponatremia or antidiuretic hormone abnormalities.
  • Significant improvement was observed following antidepressant treatment.

Conclusions:

  • Psychogenic polydipsia can occur in the context of depression.
  • Antidepressant therapy can be effective in managing this condition.
  • Early diagnosis and treatment are crucial for favorable outcomes.