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Published on: October 24, 2018
Airway complications of pediatric extracorporeal membrane oxygenation
Nicholas J M Agar1, Robert G Berkowitz
1Department of Otolaryngology, Royal Children's Hospital, Melbourne, Australia.
Insights
Children needing extracorporeal membrane oxygenation (ECMO) have a low incidence of laryngotracheal stenosis. This study found the rate of airway stenosis in pediatric ECMO survivors to be acceptably low, suggesting ECMO is safe for pediatric patients.
Area of Science:
- Pediatric critical care medicine
- Otolaryngology
- Thoracic surgery
Background:
- Prolonged intubation is a known risk factor for laryngotracheal stenosis.
- Children requiring extracorporeal membrane oxygenation (ECMO) often have extended intubation periods.
- The risk of laryngotracheal stenosis in pediatric ECMO patients is not well-defined.
Purpose of the Study:
- To determine the incidence of laryngotracheal stenosis in children undergoing ECMO.
- To assess the rate of tracheostomy in pediatric ECMO patients.
- To evaluate the association between ECMO and airway complications.
Main Methods:
- A retrospective review of pediatric patients (<18 years) who underwent ECMO from July 2009.
- Identification of patients requiring surgical airway procedures from the extracorporeal life support database.
- Analysis of airway stenosis and tracheostomy rates in ECMO patients.
Main Results:
- Overall survival rate was 51.4% among 218 ECMO patients.
- 14 patients (6.4%) required surgical airway procedures; 11 (5.0%) needed tracheostomy.
- Clinically significant laryngotracheal stenosis occurred in 3 patients (2.7% of survivors).
Conclusions:
- The incidence of laryngotracheal stenosis in children requiring ECMO is acceptably low.
- ECMO does not appear to significantly increase the risk of airway stenosis in pediatric survivors.
- Further research may explore specific risk factors for stenosis in this population.
Objectives:
Prolonged intubation is a risk factor for the development of laryngotracheal stenosis. Children who undergo extracorporeal membrane oxygenation (ECMO) usually remain intubated for an extended period. It is unclear whether the impaired cardiorespiratory status that necessitated ECMO places these children at a higher risk of laryngotracheal stenosis. This study was performed to assess the incidences of laryngotracheal stenosis and tracheostomy in children who undergo ECMO.
Methods:
We identified all patients under 18 years of age who underwent ECMO over a 10-year period concluding July 1, 2009, by use of the extracorporeal life support database of Royal Children's Hospital, Melbourne. All children in this database who underwent either a diagnostic or a therapeutic surgical procedure on the airway were identified.
Results:
The 218 patients included in the study had an overall survival rate of 51.4%. A total of 14 patients (6.4%) required a surgical procedure on the airway, and 11 of these (5.0%) needed tracheostomy. Ten of these 14 patients (71.4%) survived; of these, 2 presented with congenital laryngotracheal stenosis, 3 developed clinically significant laryngotracheal stenosis as a likely consequence of ECMO, and 5 required tracheostomy alone for long-term ventilation. The rate of airway stenosis was 2.7% in survivors.
Conclusions:
The rate of laryngotracheal stenosis in children who require ECMO is acceptably low.
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