Related Experiment Video

Updated: May 30, 2026

Curation of Computational Chemical Libraries Demonstrated with Alpha-Amino Acids
08:21

Curation of Computational Chemical Libraries Demonstrated with Alpha-Amino Acids

Published on: April 13, 2022

Rational generation of focused chemical libraries: an update on computational approaches

Rafael Gozalbes

    Combinatorial Chemistry & High Throughput Screening
    |July 22, 2011
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery
    06:26

    Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery

    Published on: May 16, 2021

    Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source
    08:35

    Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source

    Published on: May 29, 2021

    Related Experiment Videos

    Last Updated: May 30, 2026

    Curation of Computational Chemical Libraries Demonstrated with Alpha-Amino Acids
    08:21

    Curation of Computational Chemical Libraries Demonstrated with Alpha-Amino Acids

    Published on: April 13, 2022

    Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery
    06:26

    Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery

    Published on: May 16, 2021

    Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source
    08:35

    Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source

    Published on: May 29, 2021

    Related Concept Videos

    Drug Discovery: Overview01:26

    Drug Discovery: Overview

    Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...

    Articles linked to this work by shared authors, journal, and citation graph.

    Integrated in vitro/in silico test battery for the prediction of chemical-induced cholestatic liver toxicity.

    Toxicology·2026

    Pannexin1-dependent and -independent protection by novel peptidomimetics against cardiac ischemia/reperfusion injury.

    Scientific reports·2026

    GenoITS: Implementation of an Integrated Testing Strategy workflow for genotoxicity using QSAR-based tools.

    NAM journal·2026

    Stakeholder input towards further refinement and consolidation of the alternative safety profiling algorithm (ASPA) for next generation risk assessment (NGRA).

    ALTEX·2026

    Identification and Characterization of ERK2 Dimerization Inhibitors by Integrated In Silico and In Vitro Screening.

    International journal of molecular sciences·2025

    Ontogeny of drug-induced fatty liver disease (DIFLD): from key initiating events to disease phenotypes.

    Archives of toxicology·2025

    Molecular Mechanisms of Danggui Shaoyao Powder in the Treatment of Ulcerative Colitis: A Network Pharmacology Approach with Experimental Validation.

    Combinatorial chemistry & high throughput screening·2026

    Tongnao Decoction Facilitates Angiogenesis via the VEGFA/ PI3K/AKT/JUNB Signaling Axis to Promote Stroke Recovery.

    Combinatorial chemistry & high throughput screening·2026

    Th17 Cell-Related Gene Biomarkers in Autoimmune Thyroiditis: Comprehensive Bioinformatics Analysis and In Vivo Validation.

    Combinatorial chemistry & high throughput screening·2026

    A Mini-review on the Chemical Constituents and Biological Activities of Selliguea Bory.

    Combinatorial chemistry & high throughput screening·2026

    Physicochemical Characterization and Biological Activity of Ethanol- Extracted Residue of Saussurea involucrata.

    Combinatorial chemistry & high throughput screening·2026

    Probiotic Fermentation Improves Shenzhi Decoction's Hepatoprotection via Gut-Liver Axis Modulation: A Multi-Omics Study on Acute Liver Injury.

    Combinatorial chemistry & high throughput screening·2026

    Predictive Utility of Coronary Artery Calcium Score Added to the PREVENT Atherosclerotic Cardiovascular Disease Equations.

    JAMA·2026

    Quantitative structure-retention relationships (QSRR): Effect of experimental variables on QSRR model performance in HPLC - A critical review.

    Journal of chromatography. A·2026

    Cracking the nutcracker myth: CT-based risk stratification of symptomatic left renal vein Compression.

    Abdominal radiology (New York)·2026

    Computational applications in secondary metabolite discovery (CAiSMD) 2026: focus on secondary metabolites towards drug discovery.

    Journal of cheminformatics·2026

    Benchmarking Universal Machine-Learning Interatomic Potentials for Accelerated Adsorption Energy Evaluation with DFT Single-Point Calculations.

    The journal of physical chemistry letters·2026

    CCL19 and CCL21 Display Reciprocal Dependence on R209 in ECL2 of CCR7 for Receptor Activation, Relating to Differences in the Chemokine N-Terminal Region.

    Basic & clinical pharmacology & toxicology·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us