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Updated: May 30, 2026

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner
Published on: June 6, 2025
Bilateral femoral insufficiency fractures likely related to long-term alendronate therapy
Ravindra Gudena1, Jason Werle, Kelly Johnston
1Department of Orthopedics, University of Calgary, 711B, 3607-49 ST NW, Calgary, Alberta, Canada T3A 2H3.
Abstract:
Osteoporosis-related fractures are a major public health problem and one in two women and one in four men are affected with osteoporosis-related fractures. Alendronate (Fosamax) is one of the first bisphosphonates used to treat osteoporosis effectively. Recently, however, there is a concern regarding long bone insufficiency fractures related to long-term alendronate therapy. We report a case of bilateral femoral insufficiency fractures likely related to long-term alendronate therapy, the classic symptoms, signs, and treatment of these fractures.
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