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Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model

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Streptococcus suis meningitis with bilateral sensorineural hearing loss.

Hee Jae Huh¹, Kyoung-Jin Park, Ja-Hyun Jang

¹Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

The Korean Journal of Laboratory Medicine

|July 23, 2011

Summary

Streptococcus suis meningitis is an emerging zoonotic disease, particularly in Asia. This case highlights the risk to pig handlers and the potential for severe hearing loss, emphasizing the need for public health surveillance.

Keywords:

Hearing loss Korea Meningitis Streptococcus suis

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Area of Science:

Infectious Diseases
Microbiology
Public Health

Background:

Streptococcus suis is an emerging zoonotic pathogen causing meningitis in Asia.
Human infections are linked to occupational exposure to pigs and raw pork products.
Meningitis is a common manifestation, often leading to hearing loss and vestibular issues.

Observation:

A 67-year-old pig carcass handler presented with dizziness, sensorineural hearing loss, and headaches.
Cerebrospinal fluid and blood cultures revealed Gram-positive diplococci with alpha-hemolysis.
Identification was confirmed using Vitek 2, API 20 STREP, and gene sequencing (16S rRNA, tuf).

Findings:

This report details the first documented case of Streptococcus suis meningitis in Korea.
The patient experienced sensorineural hearing loss and dizziness, common sequelae of S. suis infection.
Despite antibiotic treatment, complications like hearing impairment and vestibular dysfunction are frequent.

Implications:

Highlights the importance of recognizing S. suis meningitis in at-risk populations.
Underscores the need for enhanced public health surveillance, especially for those with occupational swine exposure.
Emphasizes the potential for severe neurological complications, including hearing loss, even after treatment.