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Updated: May 30, 2026

Screening for Phytoestrogens using a Cell-based Estrogen Receptor β Reporter Assay
Published on: June 7, 2020
Phytoestrogens. State of the art
1Department of Clinical Chemistry, University of Helsinki and Institute for Preventive Medicine, Nutrition and Cancer Folkhälsan Research Center, Helsinki, Finland.
Abstract:
A short overview of recent advances of phytoestrogen research is presented. Developments have particularly been made with regard to methods, food analyses, pharmacokinetics, receptor studies, mechanisms of action and effects on cancer. Most studies deal with isoflavones, but the interest in lignans is increasing as a result of a large rye project in the Nordic countries. The development of rapid time-resolved immunofluorescence assays in 20 μl plasma samples for enterolactone, genistein and daidzein has resulted in the initiation of many prospective studies on cancer risk using blood bank material.
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