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Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Allergic Reactions02:06

Allergic Reactions

Overview
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

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Related Experiment Video

Updated: May 30, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Allergic rhinitis.

Alexander N Greiner1, Peter W Hellings, Guiseppina Rotiroti

  • 1Asthma and Allergy Centre, San Diego, CA, USA.

Lancet (London, England)
|July 26, 2011
PubMed
Summary
This summary is machine-generated.

Allergic rhinitis, often overlooked, impacts health and productivity. Effective management involves guideline-directed care, pharmacotherapy, and allergen-specific immunotherapy to improve quality of life.

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Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
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Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Related Experiment Videos

Last Updated: May 30, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Area of Science:

  • Allergology and Immunology
  • Pulmonology
  • Clinical Medicine

Background:

  • Allergic rhinitis is a prevalent condition affecting all age groups, frequently leading to underdiagnosis and mistreatment.
  • Despite not being life-threatening, it significantly impacts quality of life, productivity, and is linked to poor asthma control.
  • Current management often falls short, highlighting the need for guideline-directed approaches.

Purpose of the Study:

  • To emphasize the clinical relevance and societal costs of allergic rhinitis.
  • To review current management strategies and highlight the importance of accurate diagnosis.
  • To discuss the efficacy and safety of various treatment options for allergic rhinitis.

Main Methods:

  • Review of existing literature on allergic rhinitis diagnosis and management.
  • Analysis of pharmacotherapeutic options, including intranasal corticosteroids and immunotherapy.
  • Emphasis on diagnostic confirmation through specific IgE reactivity testing.

Main Results:

  • Intranasal corticosteroids demonstrate superiority in efficacy and safety for treating allergic rhinitis symptoms.
  • Specific IgE reactivity testing is crucial for diagnosis and guiding environmental control strategies.
  • Immunotherapy offers potential to modify the natural course of allergic rhinitis.

Conclusions:

  • Effective allergic rhinitis management requires guideline adherence, accurate diagnosis, and tailored treatment.
  • Pharmacotherapy, particularly intranasal corticosteroids, is effective, but immunotherapy holds potential for disease modification.
  • Patient education and further research are vital for improving outcomes in persistent cases.