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Updated: May 30, 2026

Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors
Published on: February 7, 2018
Oxidative stress in radiology staff
Ali Akbar Malekirad1, Akram Ranjbar, Kobra Rahzani
1Esfahan Payam-E-Noor University of Sciences, Esfahan, Iran.
Radiology workers exposed to low-dose radiation show increased oxidative stress. This suggests that precautions, like antioxidant therapy, may be beneficial for these occupationally exposed individuals.
Area of Science:
- Occupational health
- Radiation biology
- Biochemistry
Background:
- Persistent low-dose radiation exposure can induce excessive reactive oxygen species.
- This oxidative stress may lead to detrimental and irreversible outcomes in vital organs.
Purpose of the Study:
- To assess the oxidative stress status in radiology unit workers.
- Investigate the effects of persistent low-dose radiation on occupational health.
Main Methods:
- A comparative study involving 32 radiology employees and 32 controls.
- Measurement of lipid peroxidation, total antioxidant capacity, and thiol groups.
Main Results:
- Radiology workers exhibited significantly higher levels of lipid peroxidation (P=0.009).
- Elevated total antioxidant capacity (P=0.0006) and thiol groups (P=0.03) were observed in exposed individuals.
Conclusions:
- Occupationally exposed radiology personnel experience significant oxidative stress.
- Antioxidant therapy is a potentially reasonable precaution for mitigating radiation-induced oxidative damage.
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