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Related Experiment Video

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Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

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Published on: August 14, 2019

Effect of tamsulosin on ejaculatory function in BPH/LUTS.

Sang Hoon Song¹, Hwancheol Son, Kwang Taek Kim

¹Jeungpyung Health Center, Jeungpyung-gun, Chungbuk, 368-900, Korea.

Asian Journal of Andrology

|July 26, 2011

Summary

Tamsulosin (0.2 mg) showed a low incidence of ejaculatory dysfunction (EjD) after 12 weeks. Risk factors for EjD included fewer lower urinary tract symptoms and smaller prostate size.

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Area of Science:

Urology
Pharmacology

Background:

Lower urinary tract symptoms (LUTS) are common in aging males.
Alpha-blockers like tamsulosin are frequently prescribed for LUTS.
Ejaculatory dysfunction (EjD) is a known side effect of alpha-blocker therapy.

Purpose of the Study:

To assess the impact of tamsulosin (0.2 mg) on ejaculatory function over 12 weeks.
To identify risk factors associated with tamsulosin-induced ejaculatory dysfunction.

Main Methods:

A cohort of 177 men with International Prostatic Symptom Score (IPSS) ≥8 were enrolled.
Patients received tamsulosin 0.2 mg once daily for 12 weeks.
Evaluations included IPSS, Male Sexual Health Questionnaire (MSHQ), and objective measures; statistical analyses used chi-squared, t-tests, ANOVA, and logistic regression.

Main Results:

No significant changes in erectile or ejaculatory function domains were observed.
The overall incidence of ejaculatory dysfunction (EjD) was 13.4% after 12 weeks.
Higher baseline EjFD scores and fewer LUTS were associated with increased EjD incidence.

Conclusions:

Tamsulosin 0.2 mg has a low but notable incidence of EjD.
Risk factors for EjD include less severe LUTS, smaller prostate, and higher baseline sexual function scores.