Structure and function of ALG-2, a penta-EF-hand calcium-dependent adaptor protein

Masatoshi Maki1, Hironori Suzuki, Hideki Shibata

  • 1Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan. mmaki@agr.nagoya-u.ac.jp

Summary

Apoptosis-linked gene 2 (ALG-2) is a calcium-dependent adaptor protein that binds to specific proline-rich motifs. Its structure and binding properties are crucial for protein complex stabilization in cellular transport systems.

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