Related Experiment Video
Updated: May 30, 2026

04:09
The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
Published on: February 13, 2026
Atypical tumors of the rectum with pathologic correlation
Kartikeya P Kantawala1, Sushil K Sonavane, Christine O Menias
1Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA. kantawalak@mir.wustl.edu
Current Problems in Diagnostic Radiology
|July 27, 2011
Summary
This review highlights rare rectal neoplasms beyond adenocarcinoma that cause rectal bleeding. Understanding their diverse imaging features is key for accurate diagnosis and patient management.
Area of Science:
- Gastroenterology
- Oncology
- Radiology
Background:
- Rectal bleeding is a common symptom, often attributed to adenocarcinoma.
- A spectrum of rare neoplastic processes can also cause rectal bleeding.
- Accurate diagnosis of these rare lesions is essential for appropriate management.
Purpose of the Study:
- To review the clinical, imaging, and histopathologic features of rare rectal neoplasms.
- To emphasize the importance of recognizing these entities for differential diagnosis.
- To improve diagnostic accuracy and guide patient management.
Main Methods:
- Literature review of pathologically proven rectal lesions.
- Synthesis of clinical presentation, imaging findings, and histopathology.
- Focus on specific rare neoplastic entities.
Main Results:
- Detailed description of rectal carcinoid, gastrointestinal stromal tumor, cavernous hemangioma, primary anorectal melanoma, primary rectal lymphoma, and rectal metastases.
- Highlighting the diverse and sometimes non-specific imaging characteristics.
- Emphasis on distinguishing these from more common rectal pathologies.
Conclusions:
- Rare rectal neoplasms present with varied clinical and imaging findings.
- Awareness of these entities is critical for clinicians and radiologists.
- Timely and accurate diagnosis impacts treatment strategies and patient outcomes.
Related Concept Videos
Assessment of the Rectum and Anus
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Tumor Progression
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Diverticular Disease of the Colon
Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Appendicitis
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
