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[The PIG-anchoring defect of lymphocyte populations in paroxysmal nocturnal hemoglobinuria]
J Schubert1, P Uciechowski, P Delany
1Medizinische Hochschule Hannover, Abteilung Immunologie und Transfusionsmedizin.
Immunitat Und Infektion
|February 1, 1990
Abstract:
Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by a defect expression of phosphatidylinositolglycan-(PIG-)linked surface molecules. This deficiency has been demonstrated for cells of myeloid origin so far, but not for lymphocytes. In these studies we examined the defect on lymphocyte subpopulations.