[Technical methodologic aspects of clinical dosimetry in radionuclide therapy]

The paper is devoted to the solution of problems related to clinical dosimetry in radiation therapy with open radionuclides, i.e. technical methodological problems of measurement of an absorbed therapeutic dose of radiation in targets in volume distribution of a radionuclide. The developed methods and means of measurement include a large activity radiometer for measuring therapeutic and diagnostic activities, a topometric ultrasound unit (Aloka) and software. The main features of the method were illustrated on a clinical example of the assessment of an absorbed therapeutic dose of 131I radiation in thyroid tissue during therapy of patients with thyrotoxicosis. The accuracy of the method was assessed.