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Quality Assurance

Quality Assurance

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The Cultivation, Growth, and Viability of Lactic Acid Bacteria: A Quality Control Perspective

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Dietary supplement laboratory quality assurance program: the first five exercises.

Melissa M Phillips¹, Catherine A Rimmer, Laura J Wood

¹National Institute of Standards and Technology, Analytical Chemistry Division, Material Measurement Laboratory, Gaithersburg, MD 20899-8392, USA. melissa.phillips@nist.gov

Journal of AOAC International

|July 30, 2011

Summary

The National Institute of Standards and Technology (NIST) created the Dietary Supplement Laboratory Quality Assurance Program (DSQAP) to ensure accuracy in supplement analysis. This program helps laboratories demonstrate compliance with Good Manufacturing Practices.

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Last Updated: May 30, 2026

The Cultivation, Growth, and Viability of Lactic Acid Bacteria: A Quality Control Perspective

The Cultivation, Growth, and Viability of Lactic Acid Bacteria: A Quality Control Perspective

Published on: June 16, 2022

Area of Science:

Analytical Chemistry
Laboratory Science
Quality Assurance

Background:

Dietary supplements require rigorous quality control to ensure safety and efficacy.
Accurate measurement of active compounds, nutritional elements, and contaminants is crucial.
Regulatory compliance, such as Current Good Manufacturing Practices (cGMP), is essential for manufacturers.

Purpose of the Study:

To establish a comprehensive quality assurance program for laboratories analyzing dietary supplements.
To provide a framework for assessing laboratory performance in measuring key analytes.
To support the dietary supplement industry in meeting regulatory standards.

Main Methods:

NIST distributes characterized food and dietary supplement samples to participating laboratories.
Laboratories measure concentrations of specified compounds, elements, and/or markers.
NIST compiles and analyzes participant data for accuracy and concordance.

Main Results:

The Dietary Supplement Laboratory Quality Assurance Program (DSQAP) has successfully conducted five exercises.
Over 75 distinct laboratories and numerous analysts have participated.
Performance reports and certificates are issued to participants, validating their analytical capabilities.

Conclusions:

The DSQAP effectively enhances laboratory performance in dietary supplement analysis.
Participation in DSQAP aids laboratories in demonstrating adherence to cGMP standards.
The program contributes to the overall reliability and quality of dietary supplement testing.