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Related Experiment Video

Updated: May 30, 2026

In Vesiculo Synthesis of Peptide Membrane Precursors for Autonomous Vesicle Growth

In Vesiculo Synthesis of Peptide Membrane Precursors for Autonomous Vesicle Growth

Published on: June 28, 2019

Stability of growing vesicles.

Richard G Morris¹, Alan J McKane

¹Theoretical Physics, School of Physics and Astronomy, University of Manchester, Manchester, United Kingdom.

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics

|July 30, 2011

Summary

This summary is machine-generated.

We explored the stability of growing lipid vesicles using nonequilibrium thermodynamics. Two critical radii were identified, with stability depending on lipid accretion rates and perturbation type.

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Last Updated: May 30, 2026

In Vesiculo Synthesis of Peptide Membrane Precursors for Autonomous Vesicle Growth

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Membrane Remodeling of Giant Vesicles in Response to Localized Calcium Ion Gradients

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Published on: July 16, 2018

Area of Science:

Biophysics
Physical Chemistry
Nonlinear Dynamics

Background:

Vesicle stability is crucial for biological processes.
Understanding lipid bilayer dynamics is key to cell membrane function.
Nonequilibrium thermodynamics provides a framework for analyzing dynamic systems.

Purpose of the Study:

To investigate the stability of growing vesicles using nonequilibrium thermodynamics.
To identify critical radii and conditions affecting vesicle stability.
To analyze stability against axisymmetric perturbations.

Main Methods:

Utilized the formalism of nonequilibrium thermodynamics.
Modeled vesicles as discontinuous systems within linear thermodynamics.
Applied hydrodynamic descriptions of water-lipid mixtures.
Analyzed stability against arbitrary axisymmetric perturbations.

Main Results:

Identified two critical radii where stability changes occur.
Derived a physical critical radius as 2L(p)/L(γ), where L(p) is hydraulic conductivity and L(γ) is the Onsager coefficient.
Found that lower-order zonal harmonics (lower l) lead to greater instability.

Conclusions:

The study provides a theoretical framework for vesicle stability.
Lipid accretion rates and perturbation modes significantly influence stability.
Experimental validation is needed to confirm theoretical predictions.