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Related Concept Videos

Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

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Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
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Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

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Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease V: Surgical Management01:21

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Related Experiment Video

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Studying Murine Small Bowel Mechanosensing of Luminal Particulates
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Small bowel polyposis syndromes.

Nadir Arber1, Menachem Moshkowitz

  • 1Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center, 6 Weizmann St., Tel Aviv 64239, Israel. nadira@tasmc.health.gov.il

Current Gastroenterology Reports
|July 30, 2011
PubMed
Summary

This review highlights rare intestinal polyposis syndromes, focusing on Peutz-Jeghers syndrome (PJS), juvenile polyposis (JP), PTEN hamartoma tumor syndrome (PHTS), and familial adenomatous polyposis (FAP) implications in the small intestine.

Area of Science:

  • Gastroenterology
  • Genetics
  • Oncology

Background:

  • Intestinal polyposis syndromes, though rare, pose significant clinical risks.
  • Classification includes hamartomatous polyposis and familial adenomatous polyposis (FAP).
  • Small intestinal involvement is a key diagnostic consideration.

Purpose of the Study:

  • To review the clinical manifestations of common small intestinal polyposis syndromes.
  • To discuss the underlying genetic basis of these conditions.
  • To elucidate the small intestinal implications of familial adenomatous polyposis (FAP).

Main Methods:

  • Literature review of common small intestinal polyposis syndromes.
  • Focus on clinical presentation and genetic underpinnings.

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  • Analysis of Peutz-Jeghers syndrome (PJS), juvenile polyposis (JP), PTEN hamartoma tumor syndrome (PHTS), and FAP.

    • Main Results:

    • Detailed description of clinical features for PJS, JP, PHTS, and FAP.
    • Identification of key genetic mutations associated with each syndrome.
    • Emphasis on the diagnostic importance of small intestinal findings.

    Conclusions:

    • Recognition of specific small intestinal polyposis syndromes is crucial for patient management.
    • Understanding the genetics aids in diagnosis and risk assessment.
    • This review provides a comprehensive overview for clinicians managing these rare disorders.