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Updated: May 30, 2026
05:55
Modeling the Functional Network for Spatial Navigation in the Human Brain
Published on: October 13, 2023
Functional biomarkers for neurodegenerative disorders based on the network paradigm
1Brain Imaging and Modeling Section, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bldg. 10, Rm. 5D39, 10 Center Drive, MSC 1402, Bethesda, MD, USA. horwitzb@nidcd.nih.gov
Progress in Neurobiology
|August 2, 2011
Summary
Functional neuroimaging biomarkers aid in detecting and diagnosing neurodegenerative disorders. Recent research emphasizes network-based biomarkers over individual brain regions for improved assessment and treatment response evaluation.
Area of Science:
- Neuroscience
- Biomarkers
- Neuroimaging
Background:
- Neuroimaging biomarkers are crucial for understanding neurodegenerative disorders.
- Traditional biomarkers often focus on individual brain regions.
Purpose of the Study:
- To introduce the applications of functional neuroimaging biomarkers.
- To explain the shift towards network-based biomarkers in neurodegenerative research.
Main Methods:
- Review of current literature on functional neuroimaging biomarkers.
- Discussion of the advantages of network-based approaches.
Main Results:
- Functional neuroimaging biomarkers are versatile tools for detection, diagnosis, and treatment assessment.
- Network-based biomarkers offer a more comprehensive approach compared to region-specific ones.
Conclusions:
- Functional neuroimaging, particularly network-based biomarkers, shows significant promise for advancing the study and management of neurodegenerative diseases.
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