Related Experiment Video
Updated: May 30, 2026

05:03
Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy
Published on: April 17, 2020
Brain death--think twice before labeling a patient.
Rakhee Sodhi1, Sushant Khanduri, Harpal Nandha
1Department of Pulmonary Medicine, GMCH, Chandigarh, India. rakhee.sodhi@gmail.com
The American Journal of Emergency Medicine
|August 2, 2011
Summary
A snakebite victim
Area of Science:
- Neurology
- Toxicology
Background:
- Brain death signifies irreversible cessation of all brain functions.
- Neuroparalytic snake envenomation can present with symptoms mimicking brain death.
- Prompt diagnosis is crucial to avoid premature withdrawal of life support.
Observation:
- A 12-year-old boy presented with symptoms suggestive of brain death after a snakebite.
- Glasgow Coma Score was 3 with absent corneal reflexes.
- Ophthalmoplegia (internal and external) was noted, mimicking brain death.
Findings:
- The patient's condition was attributed to the neuroparalytic effects of snake venom.
- Symptoms resolved with timely administration of antivenom.
- The case underscores the importance of considering reversible causes of neurological deficits.
Implications:
- Misdiagnosis of brain death in neurotoxic envenomation can lead to tragic outcomes.
- Intensivists must consider toxicological differentials in patients presenting with apparent brain death.
- Early recognition and treatment of neuroparalytic syndromes are vital for patient survival.
Related Concept Videos
Traumatic Brain Injury l: Introduction
DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
Dementia l: Introduction
Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...

